A 69-year-old woman had an abdominal CT scan as part of a work up for proteinuria. The scan showed a cystic lesion of the head of the pancreas. CT-guided aspiration of the mass returned cuboidal and columnar epithelial cells with positive mucin staining. The amylase content of the fluid was low.
The CT scan also showed multiple calcifications throughout the body of the pancreas. The patient had no history of pancreatitis or alcohol abuse. She had no symptoms of pancreatic exocrine insufficiency, but she was a non-insulin-dependent diabetic. The remainder of the workup was negative.
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With a presumptive diagnosis of mucinous cystadenoma / cystadenocarcinoma, the patient underwent abdominal exploration for a possible Whipple procedure (pancreaticoduodenectomy). The abdomen was opened through a chevron incision. The cystic mass was palpable in the head of the pancreas. Exploration revealed no evidence of metastatic disease. No further biopsy of the lesion was done prior to beginning the evaluation of technical resectability.
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