c l i n i c a l f o l i o s : n a r r a t i v e





A D V E R T I S E M E N T

 

Early Heart Formation: 1

A D V E R T I S E M E N T

   
 

In the fourth week of embryonic life (post ovulatory days 21-28) a primitive tubular heart forms from paired primordia, begins pumping, and folds three-dimensionally to set the stage for septum formation and remodeling.       

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Early Heart Formation: 2

A D V E R T I S E M E N T

   
 

The embryonic vesicle consists of an outer chorion attached to the uterine endometrium, and the enclosed embryonic disc attached at its margins to the dome-like amnion above and to the yolk sac below. The lining of the amnion is continuous with the ectoderm of the upper surface of the embryo, and the lining of the yolk sac is continuous with the endoderm on the undersurface of the embryo. Mesoderm lies between the two layers.      

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Early Heart Formation: 3

A D V E R T I S E M E N T

   
 

By the end of the third week, the head fold rises at the cephalic end of the embryo and the lateral edges of the embryo begin to roll under. Cavities appear and coalesce in the mesoderm, splitting this layer into a dorsal somatic and a ventral splanchnic layer. This space (coelom) takes the shape of a horseshoe around the cephalic end of the embryo. This space is the beginning or the pericardial, pleural and peritoneal cavities. The oropharyngeal membrane lies immediately caudal to the pericardial region. Angioblastic tissue beneath the splanchnic layer of the presumptive pericardial cavity is called the cardiogenic plate.    

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This page was last modified on 5/28/1999.