Inflammatory conditions such as the ones listed can cause regional lymphadenopathy. However, in an adult, Hayes Martin's dictum is good to keep in mind: An asymptomatic solitary lateral neck mass in an adult is metastatic disease until proven otherwise.
The rule of 80s for solitary adult neck masses excluding thyroid is that 80% of them are malignant, and 80% of malignancies are metastatic. 80% of these come from a primary above the clavicle and 80% of them are squamous carcinoma.
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