A 62-year-old woman was incidentally noted to have a subtle low attenuation lesion in the periphery of the right lobe of the liver on a CT scan done for other reasons. The enhanced image shows the lesion more clearly. She had a history of oral hormone therapy. CT guided fine needle aspiration of the lesion was non-specific, with no malignant cells identified. The patient was taken to the operating room for elective resection of the lesion with a presumed diagnosis of hepatic adenoma. The indication for surgery was both diagnostic to rule out malignancy and prophylactic to eliminate the possibility of rupture and hemorrhage.